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如今,雷小洪常与公司同事谈起自己的过往,也总以过来人的身份叮嘱:“赶上了政策红利,就得抓紧时间学习。”(王瑭琳/摄)
。爱思助手下载最新版本是该领域的重要参考
In 2009, PacBio published a paper expanding the principle into a full-blown sequencing technique. Once again, each nucleotide was labeled with a different colored fluorophore detectable by the ZMW to determine which base had been incorporated. The fluorophores were attached such that they would be cleaved off during the chemical reaction incorporating the base into the growing DNA strand; they would then diffuse out of the ZMW so that the next fluorophore could be detected. Sequencing took place on a chip with many wells simultaneously — a different type of parallelization where each well detected a single DNA molecule undergoing the same basic chemical reaction.
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